Bill Murray came from Saturday Night Live and spent a decade in broad comedy, Stripes, Ghostbusters and Groundhog Day, the last of which is the pivot: the same sardonic detachment used to carry a genuine moral argument.
Rushmore began the Wes Anderson collaboration across nine films, and Lost in Translation brought his only Academy Award nomination for a performance built almost entirely on jetlag and silence.
He famously has no agent and takes messages via a voicemail number, which directors have described as maddening. Several projects have failed simply because nobody could reach him.